Jan Macher

Jan Macher

I am a molecular ecologist with a strong interest in biodiversity. In my research I use a combination of ecological and molecular tools to understand how stressors impact on all levels of biodiversity, from ecosystems to genes. I am especially interested in how biodiversity changes along ecological gradients, and I use genetic information obtained through barcoding, metabarcoding and metagenomic sequencing to infer the diversity of species and communities.


Molecular ecology, Metabarcoding, Metagenomics, Biomonitoring, Communities, Stress response, Ecological gradients

Dr. Jan- Niklas Macher

Postdoctoral researcher
Marine biodiversity

+31 (0)71 751 9600


  • Macher, J. N., Salis, R. K., Blakemore, K. S., Tollrian, R., Matthaei, C. D., & Leese, F. (2016). Multiple-stressor effects on stream invertebrates: DNA barcoding reveals contrasting responses of cryptic mayfly species. Ecological Indicators61, 159-169.
  • Macher, J. N., Vivancos, A., Piggott, J. J., Centeno, F. C., Matthaei, C. D., & Leese, F. (2018). Comparison of environmental DNA and bulk‐sample metabarcoding using highly degenerate cytochrome c oxidase I primers. Molecular ecology resources18(6), 1456-1468.
  • Weigand, A. M., & Macher, J. N. (2018). A DNA metabarcoding protocol for hyporheic freshwater meiofauna: Evaluating highly degenerate COI primers and replication strategy. Metabarcoding and Metagenomics2, e26869.
  • Macher, J. N., Rozenberg, A., Pauls, S. U., Tollrian, R., Wagner, R., & Leese, F. (2015). Assessing the phylogeographic history of the montane caddisfly Thremma gallicum using mitochondrial and restriction‐site‐associated DNA (RAD) markers. Ecology and evolution5(3), 648-662.
  • Macher, J. N., Zizka, V. M. A., Weigand, A. M., & Leese, F. (2018). A simple centrifugation protocol for metagenomic studies increases mitochondrial DNA yield by two orders of magnitude. Methods in Ecology and Evolution9(4), 1070-1074.

All publications on GoogleScholar